877459-63-7
877459-63-7
Chemical Structure
Leukotriene B4 ethanolamide
Synonym(s): LTB4 ethanolamide
- CAS No.: 877459-63-7
- Formula:C22H37NO4
- Molecular Weight:379.53
IUPAC Name: (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide
InChIKey: DQLVVNIINUTUIU-XLFGVTECSA-N
SMILES: CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(NCCO)=O
Biological Activity: Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) receptor 1 (BLTR1). Leukotriene B4 ethanolamide ameliorates the tumor progression, which is only asscociated with inflammation[1][2].
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Leukotriene B4 ethanolamide | Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) receptor 1 (BLTR1). Leukotriene B4 ethanolamide ameliorates the tumor progression, which is only asscociated with inflammation. | |||||||||||||||||||||
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References
- [1]. McHugh D, et al., Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors. J Pharmacol Exp Ther. 2006 Feb;316(2):955-65. [Content Brief]
- [2]. Bachi AL, et al., Leukotriene B4 creates a favorable microenvironment for murine melanoma growth. Mol Cancer Res. 2009 Sep;7(9):1417-24. [Content Brief]
Keywords
