1. Apoptosis
  2. Ferroptosis
  3. Liproxstatin-1 hydrochloride

Liproxstatin-1 hydrochloride 

Cat. No.: HY-12726A
Handling Instructions

Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM).

For research use only. We do not sell to patients.

Liproxstatin-1 hydrochloride Chemical Structure

Liproxstatin-1 hydrochloride Chemical Structure

CAS No. : 2250025-95-5

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Description

Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1].

In Vitro

Liproxstatin-1 shows antiferroptotic activity with an IC50 of approximately 38 nM in mouse embryonic fibroblasts[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Liproxstatin-1 (10 mg/kg, i.p.) suppresses ferroptosis in human cells, Gpx4-/- kidney and in an ischaemia/reperfusion-induced tissue injury model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

377.31

Formula

C₁₉H₂₂Cl₂N₄

CAS No.

2250025-95-5

SMILES

ClC1=CC(CNC(C23CCNCC2)=NC4=C(N3)C=CC=C4)=CC=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Liproxstatin-1Liproxstatin1Liproxstatin 1FerroptosisInhibitorinhibitorinhibit

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Product Name:
Liproxstatin-1 hydrochloride
Cat. No.:
HY-12726A
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