2. Membrane Transporter/Ion Channel
  3. Monoamine Transporter
  4. Lortalamine

Lortalamine (LM 1404) is a selective norepinephrine transporter inhibitor with an IC50 of <1 nM. Lortalamine is a non-tricyclic antidepressant. Lortalamine antagonises Reserpine (HY-N0480)-induced ptosis and hypothermia. Lortalamine inhibits norepinephrine uptake.

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Lortalamine

Lortalamine Chemical Structure

CAS No. : 70384-91-7

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Lortalamine Related Antibodies

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Description

Lortalamine (LM 1404) is a selective norepinephrine transporter inhibitor with an IC50 of <1 nM. Lortalamine is a non-tricyclic antidepressant. Lortalamine antagonises Reserpine (HY-N0480)-induced ptosis and hypothermia. Lortalamine inhibits norepinephrine uptake[1][2].

IC50 & Target

IC50: <1 nM (norepinephrine transporter)[1]
Molecular Weight

292.76

Formula

C15H17ClN2O2
CAS No.
SMILES

O=C1N[C@@]23[C@@](CN(CC3)C)([H])[C@](C1)([H])C4=CC(Cl)=CC=C4O2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lortalamine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lortalamine70384-91-7LM 1404LM1404LM-1404Monoamine TransporterInhibitorinhibitorinhibit

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HY-106604
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