LZ-007
LZ-007 is an agonist for farnesoid X receptor (FXR) with an EC50 of 51 nM measuring by TR-FRET assay, or an EC50 of 76 nM in HepG2 cell. LZ-007 exhibits good pharmacokinetic characheristics in SD rats. LZ-007 ameliorates western diet and CCl4 (HY-Y0298)-induced mice metabolic dysfunction-associated steatohepatitis
For research use only. We do not sell to patients.
- CAS No.: 2920000-23-1
- Formula: C27H29F3N2O5
- Molecular Weight:518.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: FXR (51 nM)
Chemical Information
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CAS No. 2920000-23-1
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Molecular Weight 518.52
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Formula C27H29F3N2O5
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SMILES
CC(C)C1=C(CN2CCC(COC3=CC=C(C(O)=O)C=C3)CC2)C(C4=CC=CC=C4OC(F)(F)F)=NO1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)