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United States

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Cat. No.: HY-172975

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MMV1578877

MMV1578877 is a Mycobacterium ulcerans inhibitor (IC₅₀: 0.37 μM). MMV1578877 can be used in the study of Buruli ulcer (BU).

For research use only. We do not sell to patients.

Formula: C₁₆H₁₂N₆S
Molecular Weight:320.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MMV1578877 Chemical Structure

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Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MMV1578877 is a Mycobacterium ulcerans inhibitor (IC₅₀: 0.37 μM). MMV1578877 can be used in the study of Buruli ulcer (BU)^[1].

Chemical Information

Molecular Weight 320.37
Formula C₁₆H₁₂N₆S
SMILES

CC1=CC(C2=NC(NC3=NC=NC=C3)=C4C(C=CS4)=N2)=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Keumoe R, et al. Discovery and structure–activity relationship analysis of 2-Pyridyl Thieno [3, 2-d] pyrimidine derivatives as promising therapeutic candidates for the treatment of Buruli ulcer[J]. bioRxiv, 2025: 2025.05. 12.653443.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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