Scotanamine D
Scotanamine D (N1-Dihydrocaffeoyl, N10-caffeoyl spermidine) is a spermidine alkaloid. It can be isolated from S. tangutica. Scotanamine D potently and selectively inhibits the activity of the M1 muscarinic acetylcholine receptor, with an IC50 of 32 nM. It can be used in studies related to Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1698873-84-5
- Formula: C25H33N3O6
- Molecular Weight:471.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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mAChR1 32 nM (IC50) |
Scotanamine D (32 nM-10 μM; 10 min) potently inhibits Carbacol-induced activity of the recombinant human M1 muscarinic acetylcholine receptor in CHO-M1 cells with an IC50 of 32 nM, and shows no activity in ORL-1 receptor-expressing HEK293T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1698873-84-5
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Molecular Weight 471.55
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Formula C25H33N3O6
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SMILES
OC(C=C1/C=C/C(NCCCNCCCCNC(CCC2=CC(O)=C(C=C2)O)=O)=O)=C(C=C1)O
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Synonyms
N1-Dihydrocaffeoyl, N10-caffeoyl spermidine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)