Neuraminidase, arthrobacter ureafaciens
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Neuraminidase, arthrobacter ureafaciens is a neuraminidase derived from Arthrobacter ureafaciens. Neuraminidase, arthrobacter ureafaciens catalyzes the removal of sialic acid residues from cell surfaces and viral glycoconjugates. Neuraminidase, arthrobacter ureafaciens enhances HIV-1-mediated syncytium formation and promotes the viral binding and entry steps in the HIV-1 replication cycle.
For research use only. We do not sell to patients.
- CAS No.: 9001-67-6
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 |
Neuraminidase from *Arthrobacter ureafaciens* (0.01 U/mL; 16 h) enhances HIV-1-mediated syncytium formation in 1G5/J1.1, Jurkat E6.1/J1.1, and PHA/IL-2-stimulated PBMC/J1.1 cell mixtures, and this effect is observed after 16 h of incubation[1].
Neuraminidase from *Arthrobacter ureafaciens* (0.01 U/mL; 16 h) enhances HIV-1-induced syncytium formation in the 1G5/J1.1 cell mixture. This effect depends on the interaction between gp120 and CD4/chemokine co-receptors, and becomes observable after 16 h of incubation[1].
Neuraminidase from *Arthrobacter ureafaciens* (0.1 U/mL; 120 min) enhances the adhesion and invasion of HIV-1 to Jurkat cells, increasing the level of viral internalization by 5-fold[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9001-67-6
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Neuraminidase, arthrobacter ureafaciens]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)