NLRP3-IN-55
NLRP3-IN-55 (Compound 19) is a potent NLRP3 inhibitor (IC50 = 0.34 μM). NLRP3-IN-55 directly targets the NLRP3 protein (KD = 0.45 μM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis.
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- Formule: C32H30ClFN2O4
- Masse moléculaire:561.04
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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NLRP3 0.34 μM (IC50) |
NLRP3 0.45 μM (Kd) |
Chemical Information
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Masse moléculaire 561.04
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Formule C32H30ClFN2O4
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SMILES
CCC(NC1=CC=C(C=C1)C2=CC=CC=C2N(C(C3=CC=C(C=C3)F)=O)CC4=CC(Cl)=CC=C4OCCOC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-55 Related Classifications
HY-169227 Related Classifications
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