NorA-IN-2
NorA-IN-2 (compound DZ-3) is a potent NorA inhibitor. NorA-IN-2 shows NorA efflux pump inhibitors (EPI) activity.
For research use only. We do not sell to patients.
- Formula: C22H24ClN3
- Molecular Weight:365.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NorA-IN-2 (compound DZ-3) shows antimicrobial activity with MICs of 8, 256, 128, 128 µg/mL for Staphylococcus aureus (S. aureus) 1199B, S. aureus RN4220,S. aureus XU212, E. coli AG100, respectively[1].
NorA-IN-2 (300, 400, 500 µg/mL; 24 h) shows cytotoxicity for RAW 264.7, HaCaT cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:RAW 264.7, HaCaT cells
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Concentration:300, 400, 500 µg/mL
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Incubation Time:24 h
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Result:Showed cytotoxicity with the viability dropped to 55 % and about 15 % in RAW 264.7 cells at 400 and 500 μg/ml respectively, 9% at concentration of 500 μg/ml in HaCaT cells.
Chemical Information
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Molecular Weight 365.90
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Formula C22H24ClN3
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SMILES
CCCCCNC1=C(N=C2C=CC=CN21)C3=C(C4=CC=CC=C4CC3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NorA-IN-2 Related Classifications
HY-163454 Related Classifications
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