1. GPCR/G Protein Neuronal Signaling
  2. 5-HT Receptor
  3. NPS ALX Compound 4a

NPS ALX Compound 4a est un antagoniste des récepteurs 5-hydroxytryptamine6 (5-HT6) qui est puissant et sélectif , avec un IC< sub>50 de 7,2 nM et un Ki de 0,2 nM.

NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.

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NPS ALX Compound 4a

NPS ALX Compound 4a Estructura química

No. CAS : 299433-10-6

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Descripciòn

NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM[1].

IC50 & Target[1]

5-HT6 Receptor

 

5-HT6 Receptor

7.2 nM (IC50)

5-HT6 Receptor

0.2 nM (Ki)

Peso molecular

431.55

Fòrmula

C25H25N3O2S

No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=S(N1C=CC2=C1C=C(N3CC(CCC4)N4CC3)C=C2)(C5=C6C=CC=CC6=CC=C5)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
NPS ALX Compound 4a
Cat. No.:
HY-103090
Cantidad:
MCE Japan Authorized Agent: