6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists

  • Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21. doi: 10.1016/s0960-894x(00)00320-6.
M Isaac  1 ,  A Slassi ,  T Xin ,  N MacLean ,  J Wilson ,  K McCallum ,  H Wang ,  L Demchyshyn
Affiliations
PMID: 10937732 DOI: 10.1016/s0960-894x(00)00320-6
Abstract

A novel series of 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives was synthesized and found to be potent and selective 5-HT6 receptor antagonists.

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