NSCLC-IN-1
NSCLC-IN-1 (Compound A10-2) induces mitophagy and ferroptosis through targeting transmembrane BAX inhibitor motif containing 6 (TMBIM6). NSCLC-IN-1 induces mitochondrial Ca2+ imbalance, leading to mitochondrial damage. NSCLC-IN-1 reduces intracellular glutathione (GSH), increases the accumulation of lipid peroxides (LPO) and malondialdehyde (MDA) content. NSCLC-IN-1 is a potent anti-NSCLC agent.
For research use only. We do not sell to patients.
- Formula: C46H56N2O13
- Molecular Weight:844.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 844.94
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Formula C46H56N2O13
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SMILES
O=C(O[C@H]1C(C)=C[C@]23[C@]1(O)[C@H](O)C(COC(C4=CC=C([N+]([O-])=O)C=C4)=O)=CC(C3=O)([H])[C@@]5([H])[C@@](C5(C)C)(OC(CCCCCCCCCCC)=O)C[C@H]2C)C6=CC=C([N+]([O-])=O)C=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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