PROTAC IRAK4 degrader-10
PROTAC IRAK4 degrader-10 (compound 10) is an oral active PROTAC based on Cereblon ligand, and induces the degradation of IRAK4 with maximum degradation of 95.94% and the DC50 of 7.68 nM in HEK293 cells (Sturcture Note:(Blue: Cereblon ligand, Black: linker；Pink: IRAK4 ligand).
For research use only. We do not sell to patients.
- CAS No.: 3033829-95-4
- Formula: C43H45F3N8O6
- Molecular Weight:826.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 3033829-95-4
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Molecular Weight 826.86
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Formula C43H45F3N8O6
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SMILES
O=C(C1=NC(C2C(F)(F)C2)=CC=C1)NC3=CN4C(C(F)=C3C(C)(O)C)=NC(C5CCN(CC6CCN(C7=CC8=C(C(N(C(CC9)C(NC9=O)=O)C8=O)=O)C=C7)CC6)CC5)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC IRAK4 degrader-10 Related Classifications
HY-158758 Related Classifications
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