Tyromycin A: a novel inhibitor of leucine and cysteine aminopeptidases from Tyromyces lacteus

  • Planta Med. 1992 Feb;58(1):56-9. doi: 10.1055/s-2006-961390.
W Weber  1 ,  M Semar ,  T Anke ,  M Bross ,  W Steglich
Affiliations
  • 1. Lehrbereich Biotechnologie, Universität Kaiserslautern, Federal Republic of Germany.
PMID: 1620745 DOI: 10.1055/s-2006-961390
Abstract

Tyromycin A, a new inhibitor of leucine and cysteine aminopeptidases has been isolated from mycelial cultures of the basidiomycete Tyromyces lacteus (Fr.) Murr. Its structure was established as 1,16-bis-[4-methyl-2,5-dioxo-3-furyl]hexadecane (1) by spectral analysis and transformation into ester and imide derivatives.

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