Bioactive constituents from roots of Bursera tonkinensis

  • Phytochemistry. 2005 Dec;66(23):2745-51. doi: 10.1016/j.phytochem.2005.09.025.
Aranya Jutiviboonsuk  1 ,  Hongjie Zhang ,  Ghee Teng Tan ,  Cuiying Ma ,  Nguyen Van Hung ,  Nguyen Manh Cuong ,  Nuntavan Bunyapraphatsara ,  D Doel Soejarto ,  Harry H S Fong
Affiliations
  • 1. Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Si Ayutthaya Road, Ratchathewi District, Bangkok 10400, Thailand.
PMID: 16289147 DOI: 10.1016/j.phytochem.2005.09.025
Abstract

Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.

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