4-Demethyldeoxypodophyllotoxin 4-O-β-D-glucopyranoside
4-Demethyldeoxypodophyllotoxin 4-O-β-D-glucopyranoside is an aryltetralin lignan glycoside that occurs in Bursera tonkinensis. It is used in studies of natural products, lignan glycosides and structure-cytotoxicity relationships.
For research use only. We do not sell to patients.
- CAS No.: 78178-42-4
- Formula: C27H30O12
- Molecular Weight:546.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.87 μM
Compound: 16
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Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
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[PMID: 21570846] |
| KB | IC50 |
2.09 μM
Compound: 16
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Cytotoxicity against human KB cells after 72 hrs by MTT assay
Cytotoxicity against human KB cells after 72 hrs by MTT assay
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[PMID: 21570846] |
In Vitro
4-Demethyldeoxypodophyllotoxin 4-O-β-D-glucopyranoside (compound 5) (100 μg/mL; 72 h) exhibits no cytotoxicity against KB human oral epidermoid carcinoma cells, LNCaP human prostate cancer cells, and Col2 human colon cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human oral epidermoid carcinoma (KB) cells, human prostate cancer (LNCaP) cells, human colon cancer (Col2) cells
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Concentration:100 μg/mL
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Incubation Time:72 h
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Result:Showed no cytotoxic activity against KB, LNCaP, or Col2 cell lines, with cell growth remaining at control levels.
Chemical Information
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CAS No. 78178-42-4
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Molecular Weight 546.52
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Formula C27H30O12
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SMILES
O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C5=CC(OCO6)=C6C=C5C[C@@]2([H])CO1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Demethyldeoxypodophyllotoxin 4-O-β-D-glucopyranoside Related Classifications
HY-N21546 Related Classifications
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