Lithocholic acid analogues, new and potent alpha-2,3-sialyltransferase inhibitors
- Chem Commun (Camb). 2006 Feb 14;(6):629-31. doi: 10.1039/b514915k.
Affiliations
- 1. Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan.
PMID: 16446832
DOI: 10.1039/b514915k
Abstract
A new type of noncompetitive alpha-2,3-sialyltransferase inhibitor has been synthesized; we report the discovery, preparation and inhibitory activity of sixteen lithocholic acid analogues.
Products
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Cat. No.Product NameDescriptionTargetResearch Area
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target: Glutathione S-transferaseResearch Areas: Cancer
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target: Sialyltransferase