High-resolution nuclear magnetic resonance spectroscopy studies of polysaccharides crosslinked by sodium trimetaphosphate: a proposal for the reaction mechanism

  • Carbohydr Res. 2007 May 21;342(7):943-53. doi: 10.1016/j.carres.2007.01.011.
Stéphane Lack  1 ,  Virginie Dulong ,  Luc Picton ,  Didier Le Cerf ,  Eric Condamine
Affiliations
  • 1. UMR 6522, CNRS-Université de Rouen, Laboratoire Polymères, Biopolymères et Membranes, F-76821 Mont Saint Aignan, France.
PMID: 17303095 DOI: 10.1016/j.carres.2007.01.011
Abstract

An NMR spectroscopy study ((31)P, (1)H, (13)C) of the postulated crosslinking mechanism of sodium trimetaphosphate (STMP) on Polysaccharides is reported using methyl alpha-D-glucopyranoside as a model. In a first step, reaction of STMP with Glc-OMe gives grafted sodium tripolyphosphate (STPP(g)). On the one hand, STTP(g) can react with a second alcohol functionality to give a crosslinked monophosphate. On the other hand, a monophosphate (grafted phosphate) could be obtained by alkaline degradation of STPP(g). NMR spectroscopy allows to detect the various species formed and to obtain the crosslinking density of STMP-polysaccharides hydrogels.

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