Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction

  • Org Lett. 2008 Jun 19;10(12):2357-60. doi: 10.1021/ol800206x.
Hong Zheng  1 ,  Gui-Qin Shang ,  Shi-Yao Yang ,  Xia Gao ,  Jin-Gou Xu
Affiliations
  • 1. Key Laboratory of Analytical Sciences, Ministry of Education, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China. [email protected]
PMID: 18484726 DOI: 10.1021/ol800206x
Abstract

A new fluorogenic and chromogenic probe rhodamine B spirolactam (1) was developed that in aqueous solutions exhibited a highly selective and sensitive "turn-on" type spectral response toward NO detection following a NO-induced spiro-ring opening reaction in 1.

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