Marine natural products: pyrrololactams from several sponges

  • J Nat Prod. 1985 Jan-Feb;48(1):47-53. doi: 10.1021/np50037a008.
F J Schmitz ,  S P Gunasekera ,  V Lakshmi ,  L M Tillekeratne
PMID: 2861253 DOI: 10.1021/np50037a008
Abstract

Two pyrrololactams, likely degradation products of more complex known guanidines, were isolated from several marine sponges. 5-Bromo- and 4,5-dibromopyrrole-1-carboxylic acid methyl esters were also isolated. A complex guanidine metabolite, poorly soluble in DMSO, was found to give sharp, reproducible nmr spectra in acid media.

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