Methyl 5-bromo-1H-pyrrole-2-carboxylate
Based on 1 Customer Validation
Methyl 5-bromo-1H-pyrrole-2-carboxylate (Compound 7) is a pyrrole that can be isolated from marine sponges Lissodendotyx sp.
For research use only. We do not sell to patients.
- Purity : 98.43%
- CAS No.: 934-07-6
- Formula: C6H6BrNO2
- Molecular Weight:204.02
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-W007392
Methyl 4-bromo-1H-pyrrole-2-carboxylate -
HY-W006646R
Methyl 5-bromo-1H-pyrrole-2-carboxylate (Standard) -
HY-107690
DMPO -
HY-Y1275
N-Methylpyrrolidone -
HY-W004756
3,4-Dibromo-1H-pyrrole-2,5-dione -
HY-32959
N-Boc-2-pyrroleboronic acid -
HY-W012956
2-Acetylpyrrole -
HY-W104848
4-Maleimidobenzoic acid -
HY-77817
Pyrrole-2-carboxaldehyde -
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1-Phenylpyrrole -
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2,5-Dimethylpyrrole -
HY-W012802
Methyl 1H-pyrrole-2-carboxylate
Biological Activity
Description
Chemical Information
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CAS No. 934-07-6
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Appearance Solid
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Molecular Weight 204.02
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Formula C6H6BrNO2
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Color White to off-white
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SMILES
COC(C(N1)=CC=C1Br)=O
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Structure Classification
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Initial Source
sponge
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (490.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (24.51 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (24.51 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9015 mL | 24.5074 mL | 49.0148 mL | 122.5370 mL |
| 5 mM | 0.9803 mL | 4.9015 mL | 9.8030 mL | 24.5074 mL | |
| 10 mM | 0.4901 mL | 2.4507 mL | 4.9015 mL | 12.2537 mL | |
| 15 mM | 0.3268 mL | 1.6338 mL | 3.2677 mL | 8.1691 mL | |
| 20 mM | 0.2451 mL | 1.2254 mL | 2.4507 mL | 6.1269 mL | |
| 25 mM | 0.1961 mL | 0.9803 mL | 1.9606 mL | 4.9015 mL | |
| 30 mM | 0.1634 mL | 0.8169 mL | 1.6338 mL | 4.0846 mL | |
| 40 mM | 0.1225 mL | 0.6127 mL | 1.2254 mL | 3.0634 mL | |
| 50 mM | 0.0980 mL | 0.4901 mL | 0.9803 mL | 2.4507 mL | |
| 60 mM | 0.0817 mL | 0.4085 mL | 0.8169 mL | 2.0423 mL | |
| 80 mM | 0.0613 mL | 0.3063 mL | 0.6127 mL | 1.5317 mL | |
| 100 mM | 0.0490 mL | 0.2451 mL | 0.4901 mL | 1.2254 mL |
Methyl 5-bromo-1H-pyrrole-2-carboxylate Related Classifications
HY-W006646 Related Classifications
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