Parkinson's Disease and Parkinsonism

  • Am J Med. 2019 Jul;132(7):802-807. doi: 10.1016/j.amjmed.2019.03.001.
Michael T Hayes  1
Affiliations
  • 1. Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address: [email protected].
Abstract

Parkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a common neurologic ailment. Male sex and advancing age are independent risk factors and, as the population ages, is taking an increasing toll on productivity and medical resources. There are a number of Other extrapyramidal conditions that can make the diagnosis challenging. Unlike Other neurodegenerative diseases, idiopathic Parkinson's disease has effective treatments that mitigate symptoms. Medications can improve day-to-day function and, in cases where medication does not give a sustained benefit or has significant side effects, treatments like deep brain stimulation result in improved quality of life.

Keywords
Deep brain stimulation; Parkinson's disease; Parkinsonism; Pharmacologic treatment.