Dihydrochalcones from the leaves of Lithocarpus litseifolius

  • J Asian Nat Prod Res. 2021 Sep;23(9):819-824. doi: 10.1080/10286020.2020.1786067.
Wen-Wen Wei  1  2  3 ,  Ping Wu  1 ,  Xiao-Yin You  1 ,  Jing-Hua Xue  1 ,  Liang-Xiong Xu  1 ,  Xiao-Yi Wei  1
Affiliations
  • 1. Key Laboratory of Plant Resources Conservation and Sustainable Utilization and Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
  • 2. Department of Biotechnology, Huizhou Institute of Agricultural Sciences, Huizhou 516023, China.
  • 3. School of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
PMID: 32646247 DOI: 10.1080/10286020.2020.1786067
Abstract

Three new phlorizin derivatives, 6"-O-vanilloylphlorizin (1), 6"-O-(4-hydroxybenzoyl)phlorizin (2), 6"-O-feruloylphlorizin (3), along with four known Dihydrochalcones, phlorizin (4), 3-hydroxyphlorizin, trilobatin, and 6"-O-acetylphlorizin were isolated from the leaves of Lithocarpus litseifolius. Their structures were established by analysis of extensive spectroscopic data. The new compounds were shown to be non-cytotoxic when tested against A549, HeLa, HepG2, and MCF-7 cell lines.

Keywords
Lithocarpus litseifolius; Lithocarpus polystachyus; dihydrochalcone; phlorizin.
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