1. Anti-infection
  2. Bacterial
  3. Xeruborbactam disodium

Xeruborbactam disodium  (Synonyms: QPX7728 disodium)

Cat. No.: HY-136072 Purity: 99.85% ee.: 100.00%
COA Handling Instructions

Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range.

For research use only. We do not sell to patients.

Xeruborbactam disodium Chemical Structure

Xeruborbactam disodium Chemical Structure

CAS No. : 2170848-99-2

Size Price Stock Quantity
5 mg USD 1650 In-stock
10 mg USD 2800 In-stock
25 mg USD 4800 In-stock
50 mg USD 7500 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Xeruborbactam disodium:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range[1].

In Vitro

Xeruborbactam disodium is a potent inhibitor of Class D carbapenemases from A. baumannii[1].
Xeruborbactam disodium is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam[1].
The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate Xeruborbactam disodium is a useful inhibitor for use with multiple beta-lactam antibiotics[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight









Room temperature in continental US; may vary elsewhere.


-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (352.16 mM; Need ultrasonic)

H2O : 76.67 mg/mL (270.00 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5216 mL 17.6081 mL 35.2162 mL
5 mM 0.7043 mL 3.5216 mL 7.0432 mL
10 mM 0.3522 mL 1.7608 mL 3.5216 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 66.67 mg/mL (234.79 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.85% ee.: 100.00%

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Xeruborbactam disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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