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  3. QPX7728-OH disodium

QPX7728-OH disodium 

Cat. No.: HY-136072
Handling Instructions

QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin (HY-108913) by purified class A, C and D enzymes, with Kis less than 0.1 µΜ.

For research use only. We do not sell to patients.

QPX7728-OH disodium Chemical Structure

QPX7728-OH disodium Chemical Structure

CAS No. : 2170848-99-2

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Description

QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin (HY-108913) by purified class A, C and D enzymes, with Kis less than 0.1 µΜ[1].

In Vitro

QPX7728-OH disodium potentiates Aztreonam (HY-B0129) and Tigemonam (HY-U00380) against strains expressing class A and class C enzymes, with MICs≤5 µg/mL. QPX7728-OH disodium potentiates Biapenem (HY-13573) against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 µg/mL[1].

Molecular Weight

281.94

Formula

C₁₀H₆BFNa₂O₅

CAS No.

2170848-99-2

SMILES

[O-]C(C1=C([O-][B+3]([O-])([O-])[[email protected]@-]2([H])[[email protected]]3([H])C2)C3=CC=C1F)=O.[Na+].[Na+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

QPX7728-OH disodiumBacterialeffluxbacteriainfectionclassesABCDresistanceInhibitorinhibitorinhibit

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QPX7728-OH disodium
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HY-136072
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