Contactin-3/CNTN3 Protein, Rat (HEK293, His)

Contactin-3/CNTN3 protein mediates crucial cell surface interactions in nervous system development and promotes neurite outgrowth. It interacts with PTPRG, indicating its involvement in signaling mechanisms that regulate neuronal growth and connectivity. Contactin-3/CNTN3 Protein, Rat (HEK293, His) is the recombinant rat-derived Contactin-3/CNTN3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Contactin-3/CNTN3 Protein, Rat (HEK293, His) is 1001 a.a., with molecular weight of 120-150 kDa.

Contactin-3/CNTN3 protein is involved in mediating essential cell surface interactions crucial for nervous system development. This protein also possesses neurite outgrowth-promoting activity, indicating its role in promoting the extension of neuronal processes. Additionally, Contactin-3/CNTN3 protein interacts with PTPRG, suggesting its involvement in intricate signaling mechanisms that regulate neuronal growth and connectivity.

Measured by its binding ability in a functional ELISA. When Recombinant Rat CNTN3 is present at 2 μg/mL, can bind Recombinant Human Amyloid Precursor. The ED₅₀ for this effect is 0.098 μg/mL.

Rat

HEK293

C-10*His

Q62682 (E20-G1001)

54279  [NCBI]

ELLLQGPVFVKEPSNSIFPVGSEDKKITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFAYLENFKSRMRSRVSVREGQGVVLLCGPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNARVLGSPTPLVLRSDGVMGEYEPKIELQFPETLPAAKGSTVKLECFALGNPVPQINWRRSDGMPFPTKIKLRKFNGVLEIPNFQQEDTGSYECIAENSRGKNVARGRLTYYAKPYWVQLLKDVETAVEDSLYWECRASGKPKPSYRWLKNGDALVLEERIQIENGALTIANLNVSDSGMFQCIAENKHGLIYSSAELKVLASAPDFSRNPMKKMIQVQVGSLVILDCKPSASPRALSFWKKGDTVVREQARISLLNDGGLKIMNVTKADAGIYTCIAENQFGKANGTTQLVVTEPTRIILAPSNMDVAVGESIILPCQVQHDPLLDIMFAWYFNGTLTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQNVRTVPEAIDGKTRTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAAPEVAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSWNTIPWKSSNGRLLGYEVRYWNNGGEEESSSKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNTAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKALENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARG

Approximately 120-150 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.