Contactin-3
Contactin-3 (CNTN3) is a GPI-anchored neuronal adhesion protein whose expression is largely confined to the nervous system, including motor neurons and cerebellar granule cells. It supports axonal growth and cell-cell recognition through homophilic and heterophilic Ig-domain interactions, and in motor neurons it participates in the outgrowth programs that shape neuromuscular connectivity. Coding variants in CNTN3 have been reported in families with amyotrophic lateral sclerosis and in some autism spectrum disorder cohorts, although penetrance is incomplete. Contactin-3 has additionally been described as an amyloidogenic protein in aging brain, adding relevance to neurodegeneration research.
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Contactin-3 Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
