MPZL3 Protein, Human (HEK293, His)

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Based on 1 Customer Validation

The MPZL3 protein is an important mediator of homogeneous cell-to-cell adhesion and promotes important interactions between cells. Its role in establishing connections emphasizes its importance in cellular cohesion, maintaining structural integrity, and facilitating communication between adjacent cells. MPZL3 Protein, Human (HEK293, His) is the recombinant human-derived MPZL3 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

The MPZL3 protein is an important mediator of homogeneous cell-to-cell adhesion and promotes important interactions between cells. Its role in establishing connections emphasizes its importance in cellular cohesion, maintaining structural integrity, and facilitating communication between adjacent cells. MPZL3 Protein, Human (HEK293, His) is the recombinant human-derived MPZL3 protein, expressed by HEK293 , with C-His labeled tag.

Background

MPZL3 Protein serves as a crucial mediator of homophilic cell-cell adhesion, facilitating essential interactions between cells. In its role, MPZL3 contributes to the establishment of connections that are integral to cellular cohesion. The protein's function underscores its significance in the processes involving adhesion, emphasizing its role in maintaining the structural integrity and communication between neighboring cells. The homophilic nature of MPZL3-mediated cell adhesion highlights its specificity in fostering interactions between identical molecules, elucidating its pivotal role in various biological contexts where cellular adhesion is fundamental.

MCE Validation Data

  • Purity - SDS-PAGE

    Purity - SDS-PAGE

    ≥ 95%, as determined by reducing SDS-PAGE.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-6*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • MPZL3 (L32-S158)
      Accession # Q6UWV2
    • His
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    MPZL3; Myelin Protein Zero-Like Protein 3; Myelin Protein Zero Like 3

  • AA Sequence

    LEIRADAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQYPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTERGFGTMLSS

  • Molecular Weight

    Approximately 15-19 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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