SLC19A2 Protein, Human (sf9, His, StrepⅡ, FLAG)
SLC19A2 Protein, supported by studies, crucially transports thiamine and mediates H(+)-dependent pyridoxine uptake. This dual function highlights SLC19A2's vital role in cellular processes for essential vitamin intake, emphasizing its significance in sustaining metabolic and biochemical functions. SLC19A2 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC19A2 protein, expressed by sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
SLC19A2 Protein, supported by studies, crucially transports thiamine and mediates H(+)-dependent pyridoxine uptake. This dual function highlights SLC19A2's vital role in cellular processes for essential vitamin intake, emphasizing its significance in sustaining metabolic and biochemical functions. SLC19A2 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC19A2 protein, expressed by sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.
SLC19A2 Protein takes on a pivotal role as a high-affinity transporter facilitating the uptake of thiamine, as substantiated by various studies. In addition to its role in thiamine transport, this protein also mediates H(+)-dependent pyridoxine transport, contributing to the cellular uptake of pyridoxine. This dual functionality underscores the importance of SLC19A2 in the cellular processes associated with the intake of essential vitamins, emphasizing its significance in maintaining metabolic and biochemical functions.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-StrepⅡ;N-8*His;C-Flag
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Accession
O60779 (D2-S497)
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Gene ID10560
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Molecular Construction
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N-term
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8*His-StrepⅡ
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SLC19A2 (D2-S497)
Accession # O60779 -
Flag
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C-term
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Protein Length
Full Length
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Synonyms
SLC19A2; Solute Carrier Family 19 Member 2 Isoform 1; Prev. TRMA; Reduced Folate Carrier Protein (RFC) Like; Thiamine Transporter 1; SLC19A2 Solute Carrier Family 19 Member 2; ThTr-1; High Affinity Thiamine Transporter; THTR1; Thiamnine Trasporter Protein; ThT1; Thiamine Transporter THTR-1; Solute Carrier Family 19 (Thiamine Transporter), Member 2; Thiamine Carrier 1; Thiamine-Responsive Megaloblastic Anaemia; THMD1; TC1; ThTr1; Solute Carrier Family 19 Thiamine Transporter Member 2; THT1; Solute Carrier Family 19 Member 2; Solute Carrier Family 19 Member 2 Isoform 2
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AA Sequence
DVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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