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Ricinoleic acid (purity≥99%) 

Cat. No.: HY-N6070A Purity: ≥98.0%
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Ricinoleic acid (purity≥99%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid has analgesic properties, pro- or anti-inflammatory effects, and antagonistic activity against the prostaglandin E3 receptor.

For research use only. We do not sell to patients.

Ricinoleic acid (purity≥99%) Chemical Structure

Ricinoleic acid (purity≥99%) Chemical Structure

CAS No. : 141-22-0

Size Price Stock Quantity
5 mg USD 32 In-stock
10 mg USD 45 In-stock
50 mg USD 70 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ricinoleic acid (purity≥99%):

Ricinoleic acid (purity≥99%) Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ricinoleic acid (purity≥99%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid has analgesic properties, pro- or anti-inflammatory effects, and antagonistic activity against the prostaglandin E3 receptor[1][2].

In Vitro

Ricinoleic acid (10-100 μM, 24 h) inhibits the release of β-HEX in RBL-2H3 cells induced by DNP-BSA in a dose-dependent manner in RBL-2H3 cells[2].
Ricinoleic acid (10-100 μM, 24 h) inhibits glucose production in a dosedependent manner in H4IIE cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ricinoleic acid (purity≥99%) Related Antibodies

Western Blot Analysis[2]

Cell Line: H4IIE cells
Concentration: 100 μM
Incubation Time: 1 h
Result: Increased the level of GSK-3β phosphorylation at Ser9.
Increased the stability of β-catenin at the protein level.
Decreased the phosphorylated GS to total GS ratio.
Molecular Weight

298.46

Formula

C18H34O3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(CCCCCCC/C=C\C[C@H](O)CCCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (335.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3505 mL 16.7527 mL 33.5053 mL
5 mM 0.6701 mL 3.3505 mL 6.7011 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (8.38 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (8.38 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3505 mL 16.7527 mL 33.5053 mL 83.7633 mL
5 mM 0.6701 mL 3.3505 mL 6.7011 mL 16.7527 mL
10 mM 0.3351 mL 1.6753 mL 3.3505 mL 8.3763 mL
15 mM 0.2234 mL 1.1168 mL 2.2337 mL 5.5842 mL
20 mM 0.1675 mL 0.8376 mL 1.6753 mL 4.1882 mL
25 mM 0.1340 mL 0.6701 mL 1.3402 mL 3.3505 mL
30 mM 0.1117 mL 0.5584 mL 1.1168 mL 2.7921 mL
40 mM 0.0838 mL 0.4188 mL 0.8376 mL 2.0941 mL
50 mM 0.0670 mL 0.3351 mL 0.6701 mL 1.6753 mL
60 mM 0.0558 mL 0.2792 mL 0.5584 mL 1.3961 mL
80 mM 0.0419 mL 0.2094 mL 0.4188 mL 1.0470 mL
100 mM 0.0335 mL 0.1675 mL 0.3351 mL 0.8376 mL
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Ricinoleic acid (purity≥99%) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ricinoleic acid (purity≥99%)141-22-0Biochemical Assay Reagentsanti-inflammatorypro-inflammatoryanalgesicprostaglandinE3 receptorRBL-2H3 cellsH4IIE cellsInhibitorinhibitorinhibit

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