SDH-IN-48
SDH-IN-48 is a succinate dehydrogenase (SDH) inhibitor, with an IC50 of 0.056 μM against porcine SDH. SDH-IN-48 binds to the SDH active pocket through multiple non-covalent interactions. SDH-IN-48 can be used in related research on rice sheath blight disease.
For research use only. We do not sell to patients.
- Formula: C21H16F6N4O2
- Molecular Weight:470.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
SDH 0.056 μM (IC50) |
In Vitro
SDH-IN-48 (compound 8r) potently inhibits porcine heart-derived succinate dehydrogenase with an IC50 of 0.056 μM and forms a stable, high-affinity complex with the enzyme via multiple favorable interactions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 470.37
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Formula C21H16F6N4O2
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SMILES
O=C(C1=C(F)N(C)N=C1C(F)F)NC2=CC=CC(/C(C3=CC=CC(C(F)(F)F)=C3)=N\OC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDH-IN-48 Related Classifications
HY-187992 Related Classifications
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