MRT2000769
MRT2000769 is a Kir7.1 inhibitor with an IC50 of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage.
For research use only. We do not sell to patients.
- CAS No.: 1214573-32-6
- Formula: C21H26FNO4
- Molecular Weight:375.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Kir7.1 2 μM (IC50) |
In Vitro
MRT2000769 (1.1-3.5 μM) potently inhibits recombinant Kir7.1 channels expressed in Chinese hamster ovary cells, with an IC50 of 2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1214573-32-6
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Molecular Weight 375.44
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Formula C21H26FNO4
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SMILES
FC1=CC=CC(OC2CCN(CC2)CC(O)C3=CC(OC)=CC=C3OC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRT2000769 Related Classifications
HY-122638 Related Classifications
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