29 Results for "

8-Hydroxyquinoline

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "8-Hydroxyquinoline" in MCE Product Catalog:

Cat. No.: HY-B0295R
CAS No.: 773-76-2
Research Areas:  

Infection

Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
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Cat. No.: HY-158104
Target:  

ATF6

Research Areas:  

Others

LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
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Cat. No.: HY-W001023A
CAS No.: 21302-43-2
Synonyms: 5A8HQ dihydrochloride; 5AHQ dihydrochloride
Target:  

Proteasome NF-κB

Research Areas:  

Cancer

5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) dihydrochloride is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline dihydrochloride can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline dihydrochloride can be used for the research of cancer, such as leukemia .
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Cat. No.: HY-W051530
CAS No.: 938-33-0
Target:  

Drug Derivative

Research Areas:  

Cancer


8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer .
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Cat. No.: HY-179044
CAS No.: 3100092-62-1
Research Areas:  

Cancer

MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator. MKK7-JNK activator 1 effectively inhibits the proliferation and migration of MDA-MB-468 cells, induces G2/M phase arrest and caspase -dependent apoptosis (independent of ROS production). MKK7-JNK activator 1 significantly increases the levels of p-MKK7 and p-JNK, but does not affect p-ERK or p-p38. MKK7-JNK activator 1 can be used for the study of triple-negative breast cancer (TNBC) .
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Cat. No.: HY-P11783
CAS No.: 86711-55-9
Target:  

Fungal

Research Areas:  

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
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Cat. No.: HY-W989128
CAS No.: 686723-15-9
Ethyl 8-hydroxy-α-(2-propynylamino) is a bifunctional iron chelator that inhibits lipid peroxidation (IC50 = 15 μM). Ethyl 8-hydroxy-α-(2-propynylamino) chelates Fe (II) and Fe (III) metal ions, and inhibits iron/ascorbic acid-induced mitochondrial membrane lipid peroxidation. Ethyl 8-hydroxy-α-(2-propynylamino) can be used in the research of oxidative stress and neurodegenerative diseases .
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Cat. No.: HY-P2209
CAS No.: 53947-96-9
Synonyms: Daechuine S27; N-Demethylamphibine H
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
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Cat. No.: HY-P4948
CAS No.: 1926163-49-6
Research Areas:  

Others

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
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