21302-43-2
Chemical Structure
5-Amino-8-hydroxyquinoline dihydrochloride
Synonym(s): 5A8HQ dihydrochloride; 5AHQ dihydrochloride
- CAS No.: 21302-43-2
- Formula:C9H10Cl2N2O
- Molecular Weight:233.09
IUPAC Name: 5-aminoquinolin-8-ol dihydrochloride
InChIKey: VTQDJAUGGZFPOI-UHFFFAOYSA-N
SMILES: NC1=CC=C(O)C2=NC=CC=C21.Cl.Cl
Biological Activity: 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) dihydrochloride is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline dihydrochloride can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline dihydrochloride can be used for the research of cancer, such as leukemia[1].
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5-Amino-8-hydroxyquinoline dihydrochloride | 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) dihydrochloride is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline dihydrochloride can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline dihydrochloride can be used for the research of cancer, such as leukemia. | |||||||||||||||||||||
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