686723-15-9
Chemical Structure
Ethyl 8-hydroxy-α-(2-propynylamino)
- CAS. Nr.: 686723-15-9
- Formula:C17H18N2O3
- Molecular Weight:298.34
IUPAC Name: ethyl 3-(8-hydroxyquinolin-5-yl)-2-(prop-2-yn-1-ylamino)propanoate
InChIKey: IQZXIKMXXCLFOK-UHFFFAOYSA-N
SMILES: O=C(OCC)C(NCC#C)CC=1C=CC(O)=C2N=CC=CC21
Biological Activity: Ethyl 8-hydroxy-α-(2-propynylamino) is a bifunctional iron chelator that inhibits lipid peroxidation (IC50 = 15 μM). Ethyl 8-hydroxy-α-(2-propynylamino) chelates Fe (II) and Fe (III) metal ions, and inhibits iron/ascorbic acid-induced mitochondrial membrane lipid peroxidation. Ethyl 8-hydroxy-α-(2-propynylamino) can be used in the research of oxidative stress and neurodegenerative diseases[1].
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Ethyl 8-hydroxy-α-(2-propynylamino) | Ethyl 8-hydroxy-α-(2-propynylamino) is a bifunctional iron chelator that inhibits lipid peroxidation (IC50 = 15 μM). Ethyl 8-hydroxy-α-(2-propynylamino) chelates Fe (II) and Fe (III) metal ions, and inhibits iron/ascorbic acid-induced mitochondrial membrane lipid peroxidation. Ethyl 8-hydroxy-α-(2-propynylamino) can be used in the research of oxidative stress and neurodegenerative diseases. | |||||||||||||||||||||
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Keywords
