86 Results for "

CD86

" in MedChemExpress (MCE) Product Catalog:
Products (86)

86 Results for "CD86" in MCE Product Catalog:

Cat. No.: HY-RS16645
Research Areas:  

Others

Cd86 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd86 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-169819
CAS No.: 882291-37-4
Research Areas:  

Inflammation/Immunology

Calcium influx inducer compound 634 is a calcium influx inducer. Calcium influx inducer compound 634 (10 µM) enhances the release of extracellular vesicles (EVs) from mouse bone marrow-derived dendritic cells (mBMDCs). Calcium influx inducer compound 634 (10 µM) also increases the levels of CD86 and CD80 on the surface of mBMDCs, an effect that can be blocked by the calcium release-activated calcium channel inhibitor YM-58483 (HY-100831) .
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Cat. No.: HY-152201
CAS No.: 1374239-71-0
Target:  

Btk

Research Areas:  

Cancer

BTK-IN-18 is a potent, reversible BTK inhibitor with an IC50 of 0.002 µM. BTK-IN-18 inhibits both CD69 and CD86 in vivo .
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Cat. No.: HY-P990261
Anti-Mouse CD83 Antibody (Michel-17) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD83. Anti-Mouse CD83 Antibody (Michel-17) can block CD83 and inhibit T cells proliferation. Anti-Mouse CD83 Antibody (Michel-17) can be used for the researches of cancer and immunology, such as solid tumor .
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Cat. No.: HY-148980
CAS No.: 30918-54-8
Research Areas:  

Inflammation/Immunology

Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .
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Cat. No.: HY-P991566
CAS No.: 2983061-18-1

Target:  

CTLA-4

Research Areas:  

Cancer

KD6001 is a humanized IgG1κ monoclonal antibody, targeting CTLA4. KD6001 significantly disrupts CTLA-4 interactions with CD80 (IC50: 16 ng/mL) and CD86. KD6001 enhances IL-2 and IFNγ expression in PHA-activated human lymphocytes and exhibits potent antitumor effects. KD6001 effectively inhibits tumor growth in MC38, B16, and Hepa1-6 tumor mice model. KD6001 can be used for cancers research, such as advanced melanoma, hepatocellular carcinoma and liver cancer .
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Cat. No.: HY-143410
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 16 (compound 14), a peptidomimetic, shows potent anti-inflammatory activity. Anti-inflammatory agent 16 reduces TNFα, NO, CD40 and CD86 expression level .
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Cat. No.: HY-150740
Research Areas:  

Inflammation/Immunology

ODN 21595 is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 reduces the expression of CD86 and HLA-DR. ODN 21595 has the potential for the research of systemic lupus erythematosus (SLE) .
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Cat. No.: HY-150740A
Research Areas:  

Inflammation/Immunology

ODN 21595 sodium is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 sodium inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 sodium reduces the expression of CD86 and HLA-DR. ODN 21595 sodium has the potential for the research of systemic lupus erythematosus (SLE) .
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Cat. No.: HY-P991366
Synonyms: AL008

Target:  

CD47

Research Areas:  

Cancer

IBI-397 is a human monoclonal antibody (mAb) targeting SIRPα/CD172a . IBI-397 promotes human monocyte-derived dendritic cell-mediated T cell proliferation and increases the expression of CD86 and HLA-DR. IBI-397 has antitumor activity in the mouse MDA-MB-231 tumor model. IBI-397 can be used in Myeloma research .
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Cat. No.: HY-P991908

Research Areas:  

Inflammation/Immunology

Anti-CD86 Antibody (3D1) is an antibody against human CD86. Recommend Isotype Controls:?Mouse IgG2b kappa, Isotype Control (HY-P99982).
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Cat. No.: HY-P991777

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD86/B7-2 Antibody (2D10) reacts with mouse CD86 (B7-2). Anti-Mouse CD86/B7-2 Antibody (2D10) reduces IL-4 production in T cells. Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682) .
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Cat. No.: HY-161833
CAS No.: 2117645-10-8
Research Areas:  

Inflammation/Immunology

HSP90-IN-31 (compound Be01) causes reduction of CD80 and CD86 expression on dendritic cells (DCs). HSP90-IN-31 decreases the production of pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β) in BMDC and peritoneal macrophages stimulated by LPS (HY-D1056). Under the delayed-type hypersensitivity (DTH) mice model, HSP90-IN-31 reduces ear swelling and pro-inflammatory cytokines in the spleen .
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Cat. No.: HY-W016773S
CAS No.: 347841-78-5
1,10-Decanediol-d20 is the deuterium labeled 1,10-Decanediol . 1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism. can be used as a surfactant/stabilizer in the synthesis of nanomaterials .
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Cat. No.: HY-144675
CAS No.: 2170212-33-4
Target:  

Histone Demethylase

Research Areas:  

Cancer

LSD1-IN-13 (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 induces differentiation of AML (acute myeloid leukemia) cell lines .
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Cat. No.: HY-144675A
CAS No.: 2170347-90-5
Target:  

Histone Demethylase

Research Areas:  

Cancer

LSD1-IN-13 hydrochloride (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 hydrochloride can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines .
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Cat. No.: HY-141677B
CAS No.: 2081940-67-0
Target:  

Histone Demethylase

Research Areas:  

Cancer

INCB059872 tosylate is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor that achieves inhibitory activity through the formation of covalent FAD-adducts. INCB059872 tosylate can inhibit cell proliferation and induce cell differentiation by upregulating the expression of myeloid differentiation markers CD86 and CD11b. INCB059872 tosylate can be used for the research of myeloid leukemia .
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Cat. No.: HY-160227
CAS No.: 1116698-32-8
Research Areas:  

Inflammation/Immunology

ORN 06 (Compound R-0006), a U-rich single-stranded RNA (containing 6 repeats of the UUG sequence motif), is a TLR7/8 agonist. ORN 06 stimulates human TLR7/8-mediated or murine TLR7-mediated immunity .
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Cat. No.: HY-P7635
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD86; FUN-1; Prev. CD28LG2; B70; T-Lymphocyte Activation Antigen CD86; B-Lymphocyte Activation Antigen B7-2; B7.2; B-Lymphocyte Antigen B7-2; B7-2; CD86 Antigen; CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen); CD86 V6; CTLA-4 Counter-Receptor B7.2; LA
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-150749
CAS No.: 1198621-85-0
Target:  

IFNAR

Research Areas:  

Inflammation/Immunology Cancer

ODN D-SL03 is a C class CpG oligonucleotides, can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3' .
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