1374239-71-0
1374239-71-0
Chemical Structure
BTK-IN-18
- CAS No.: 1374239-71-0
- Formula:C20H22Cl2N6O
- Molecular Weight:433.33
IUPAC Name: 1-((2R,3R)-3-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)-2-((3,5-dichlorophenyl)amino)ethan-1-one
InChIKey: HORBTILEDZCTEX-SJKOYZFVSA-N
SMILES: C[C@@H]1[C@@H](CCCN1C(CNC2=CC(Cl)=CC(Cl)=C2)=O)NC3=C4C=CNC4=NC=N3
Biological Activity: BTK-IN-18 is a potent, reversible BTK inhibitor with an IC50 of 0.002 µM. BTK-IN-18 inhibits both CD69 and CD86 in vivo[1].
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BTK-IN-18 | BTK-IN-18 is a potent, reversible BTK inhibitor with an IC50 of 0.002 µM. BTK-IN-18 inhibits both CD69 and CD86 in vivo. | |||||||||||||||||||||
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References
Keywords
