2081940-67-0
Chemical Structure
INCB059872 tosylate
- CAS 番号: 2081940-67-0
- Formula:C30H42N2O6S
- Molecular Weight:558.73
InChIKey: ZOLYYKZGDCMNJM-CMXBXVFLSA-N
SMILES: OC(C1(CCC1)CN2CCC(COC)(CC2)CN[C@H]3[C@@](C4=CC=CC=C4)([H])C3)=O.O=S(O)(C5=CC=C(C=C5)C)=O
Biological Activity: INCB059872 tosylate is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor that achieves inhibitory activity through the formation of covalent FAD-adducts. INCB059872 tosylate can inhibit cell proliferation and induce cell differentiation by upregulating the expression of myeloid differentiation markers CD86 and CD11b. INCB059872 tosylate can be used for the research of myeloid leukemia[1].
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INCB059872 tosylate | INCB059872 tosylate is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor that achieves inhibitory activity through the formation of covalent FAD-adducts. INCB059872 tosylate can inhibit cell proliferation and induce cell differentiation by upregulating the expression of myeloid differentiation markers CD86 and CD11b. INCB059872 tosylate can be used for the research of myeloid leukemia. | |||||||||||||||||||||
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