46 Results for "

CDX

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "CDX" in MCE Product Catalog:

Cat. No.: HY-RS25092
Research Areas:  

Others

Cdx2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdx2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99057A
CAS No.: 1393344-72-3
Synonyms: CDX-1127 (anti-CD27)
Varlilumab (CDX-1127) (anti-CD27) is an agonist anti-CD27 monoclonal antibody. Varlilumab (anti-CD27) can promote T cell expansion and activate the immune response. Varlilumab (anti-CD27) has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors .
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Cat. No.: HY-P990875
Synonyms: CR014; CDX-014 antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Others

Anti-TIM-1/KIM-1/CD365 Antibody (2.70.2) is antiTIM/KIM-1/CD365of antibodies.
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Cat. No.: HY-170237
CAS No.: 3038863-24-7
Research Areas:  

Cancer

SIK2/3-IN-1 (Compound 7S) is a selectively inhibitory agent of SIK2/3 with oral activity. SIK2/3-IN-1 can significantly inhibit tumor growth (without any body weight loss) in the MV4-11 AML mice CDX model. SIK2/3-IN-1 can be used in the research of MEF2C-dependent acute myeloid leukemia .
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Cat. No.: HY-P991862

Research Areas:  

Cancer

CDX-0125-TEI Antibody is an anti-human ALK antibody. AMG-224 Antibody can generate antibody drug conjugate (ADC) (CDX-0125-TEI) with thienoindole (TEI) DNA minor groove alkylating agent. CDX-0125-TEI Antibody can be used for the study of neuroblastoma .
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Cat. No.: HY-P990566
CAS No.: 1587257-96-2
Synonyms: Rasdegafusp alfa

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

CDX-1401 is a CHO-expressed human-derived antibody targeting LY75/CD205/DEC-205. CDX-1401 features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for CDX-1401 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-170968
CAS No.: 3037323-16-0
Target:  

EGFR Apoptosis

Research Areas:  

Cancer

EGFR-IN-150 is an EGFR inhibitor that effectively suppresses the phosphorylation of mutant epidermal growth factor receptor (EGFR) and its downstream AKT signaling pathway, thereby exerting antitumor effects and inducing HMOX1 expression to trigger ferroptosis. EGFR-IN-150 exhibits an IC50 of 0.386 μM against the non-small cell lung cancer (NSCLC) cell line H1975, and significantly inhibits colony formation and migration of both H1975 and A549 cells while inducing apoptosis. In addition, EGFR-IN-150 markedly suppresses tumor growth in the H1975 cell-derived xenograft (CDX) mouse model. EGFR-IN-150 holds promise for research related to non-small cell lung cancer .
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Cat. No.: HY-P992509
Synonyms: NCT02642016; KTN0158

Target:  

c-Kit

Research Areas:  

Cancer

CDX-0158 (NCT02642016; KTN0158) is a humanized anti-c-Kit/CD117 IgG1κ monoclonal antibody. CDX-0158 effectively blocks the SCF-KIT signaling pathway and inhibits mast cell activation, but due to the retention of wild-type IgG1 Fc, it can induce mast cell degranulation through FcyR cross-linking, resulting in obvious infusion reactions. CDX-0158 can be used in research related to advanced refractory gastrointestinal stromal tumors .
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Cat. No.: HY-RS18606
Research Areas:  

Others

Cdx2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdx2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84754
Synonyms: CDX3; CDX-3; CDX2/AS

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P82217
Synonyms: CDX1; Homeobox protein CDX 1

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P84754A
Synonyms: CDX3; CDX-3; CDX2/AS

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P86008

Host:  

Mouse

Application:  

IHC-P, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85655
Synonyms: CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Host:  

Mouse

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85569
Synonyms: Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; CDX2; CDX2_HUMAN; CDX3; Homeobox protein CDX 2; Homeobox protein CDX-2; Homeobox protein CDX2.

Host:  

Mouse

Application:  

WB, IP, ICC/IF

Reactivity:  

Human, Monkey

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Cat. No.: HY-P85796
Synonyms: Caudal type homeo box 2 antibody; Caudal type homeo box transcription factor 2 antibody; Caudal type homeobox 2 antibody; Caudal type homeobox protein 2 antibody; Caudal type homeobox transcription factor 2 antibody; Caudal-type homeobox protein 2 antibody; CDX 2 antibody; CDX 3 antibody; CDX-3 antibody; CDX2 antibody; CDX2/AS antibody; CDX2_HUMAN antibody; CDX3 antibody; Homeobox protein CDX 2 antibody; Homeobox protein CDX-2 antibody;

Host:  

Mouse

Application:  

IHC-P, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P80983
Synonyms: Caudal type homeo box 2 antibody; Caudal type homeo box transcription factor 2 antibody; Caudal type homeobox 2 antibody; Caudal type homeobox protein 2 antibody; Caudal type homeobox transcription factor 2 antibody; Caudal-type homeobox protein 2 antibody; CDX 2 antibody; CDX 3 antibody; CDX-3 antibody; CDX2 antibody; CDX2_HUMAN antibody; CDX3 antibody; Homeobox protein CDX 2 antibody; Homeobox protein CDX-2 antibody;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703099
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDX2; CDX-3; Prev. CDX3; Caudal Type Homeobox Transcription Factor 2; Caudal-Type Homeobox Protein 2; Homeobox Protein MiniCDX2 Variant; Homeobox Protein CDX-2; Homeobox Protein MiniCDX2; CDX2/AS; Caudal Type Homeobox 2; Caudal Type Homeo Box Transcriptio
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P87659

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-189497
CAS No.: 3133169-21-5
Target:  

CDK

Research Areas:  

Cancer

CCNE1 degrader-2 is an orally active CCNE1 degrader with a paDC50 of 7.7 nM. CCNE1 degrader-2 promotes the targeted degradation of Cyclin E1 protein. CCNE1 degrader-2 inhibits tumor cell proliferation and exerts antitumor activity in CDX in vivo models. CCNE1 degrader-2 is used in research on cancers such as ovarian cancer and breast cancer .
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