21 Results for "

GPVI

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "GPVI" in MCE Product Catalog:

Convulxin
Convulxin
0 Images
Cat. No.: HY-117123
CAS No.: 37206-04-5
Category:  

Natural Products Animals Snake Venoms Animal Venoms

Target:  

Glycoprotein VI Src Interleukin Related Reactive Oxygen Species (ROS) NOD-like Receptor (NLR) Mitochondrial Metabolism

Convulxin is a toxin found in a tropical rattlesnake. Convulxin stimulates platelet aggregation, and clusters GPVI to trigger Src family kinase activation, Fc receptor γ chain phosphorylation, and p72SYK signaling. Convulxin interacts with Dectin-2 to induce IL-10 production, activates monocytes to generate ROS and NLRP3 inflammasome-mediated IL-1β secretion, and induces mitochondrial ROS. Convulxin causes transient arterial blood pressure changes in dogs. Convulxin can be used for research related to coagulation .
loading...
    loading...
View All Sizes
Assay Types