216 Results for "

IR

" in MedChemExpress (MCE) Product Catalog:
Products (216)

216 Results for "IR" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-136886
CAS No.: 172616-80-7
Purity:  96.36%
Synonyms: New Indocyanine Green
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
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2
2 Cited Publications
Cat. No.: HY-W250113
CAS No.: 58856-93-2
Synonyms: Zymosan A from Saccharomyces cerevisiae
Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury .
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2
2 Cited Publications
Cat. No.: HY-125203
CAS No.: 1093793-05-5
Purity:  99.30%
Synonyms: NSC 744039
Research Areas:  

Cancer

PV-1019 (NSC 744039) is a potent, selective Chk2 inhibitor with an IC50 value of 24 nM. PV-1019 inhibits the Topotecan (HY-13768)-induced Chk2 autophosphorylation. PV-1019 inhibits IR-induced apoptosis .
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2 Cited Publications
Cat. No.: HY-13686
CAS No.: 196868-63-0
Purity:  99.85%
Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .
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2
2 Cited Publications
Cat. No.: HY-118530
CAS No.: 65002-17-7
Purity:  98.87%
Synonyms: SA96; Thiobutarit
Target:  

VEGFR

Bucillamine (SA96) is an orally active and potent sulfhydryl donor and antioxidant. Bucillamine is also an antirheumatic agent with antiangiogenic properties. Bucillamine can protect against Ischemia/reperfusion (I/R) injury in high-risk organ transplants. Bucillamine inhibits the production of VEGF. Bucillamine can be used for the research of choroidal neovascularization (CNV) and rheumatoid arthritis (RA) .
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1
1 Cited Publications
Cat. No.: HY-D1449
CAS No.: 155614-01-0
Target:  

Fluorescent Dye

Research Areas:  

Others

IR-1061 is a near infrared fluorescent organic dye for in vivo bimodal imaging .
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1
1 Cited Publications
Cat. No.: HY-W018499
CAS No.: 3347-90-8
(S)-2-Hydroxybutanoic acid is the S-enantiomer of 2-Hydroxybutanoic acid. 2-Hydroxybutanoic acid, a coproduct of protein metabolism, is an insulin resistance (IR) biomarker .
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1
1 Cited Publications
Cat. No.: HY-N6869
CAS No.: 1740-19-8
Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .
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1
1 Cited Publications
Cat. No.: HY-N2421
CAS No.: 523-92-2
Synonyms: 5-O-Methyl-myo-inositol
Sequoyitol (5-O-Methyl-myo-inositol) is an orally active hypoglycemic agent and antioxidant. Sequoyitol can be isolated from herbaceous plants. Sequoyitol downregulates the expression of NF-κB and TGF-β1, reduces ROS production and malondialdehyde levels, and enhances total antioxidant capacity. Sequoyitol activates the insulin signaling pathway, including the phosphorylation of IR, IRS1 and Akt. Sequoyitol increases serum insulin levels, inhibits hepatic glucose production, and promotes cellular glucose uptake. Sequoyitol antagonizes TNFα-induced inhibition of the insulin signaling pathway, and decreases blood urea nitrogen and serum creatinine levels. Sequoyitol elicits potential peaks in the chemosensors of adult and larval Atrophaneura alcinous, and acts as an oviposition stimulant for female Atrophaneura alcinous. Sequoyitol can be used in research related to type 2 diabetes, insulin resistance, hyperglycemia, impaired glucose tolerance and diabetic nephropathy .
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1 Cited Publications
Cat. No.: HY-P73873
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INSR; Receptor Protein-Tyrosine Kinase; Insulin Receptor; CD220 Antigen; CD220; HHF5; IR
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-12829
CAS No.: 1128096-91-2
Purity:  98.01%
SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor. SR-3306 is a neuroprotective agent that can be used for the study of Parkinson's disease, ischemia/reperfusion (I/R) injury and obesity .
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1 Cited Publications
Cat. No.: HY-W088089
CAS No.: 181934-09-8
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
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1
1 Cited Publications
Cat. No.: HY-P73873A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INSR; Receptor Protein-Tyrosine Kinase; Insulin Receptor; CD220 Antigen; CD220; HHF5; IR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-D1711
CAS No.: 172971-76-5
Synonyms: IR-808
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .
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Cat. No.: HY-160523
CAS No.: 2695594-15-9
Research Areas:  

Others

DBCO Ir catalyst is an iridium catalyst labeled with DBCO. DBCO Ir catalyst can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems .
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Cat. No.: HY-W008260
CAS No.: 12112-67-3
Synonyms: Chloro-1,5-cyclooctadiene IRidium(I) dimer
[Ir(cod)Cl]2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-D2189
CAS No.: 916821-46-0
Synonyms: IR 700DX NHS ester
IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer .
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Cat. No.: HY-W018845
CAS No.: 12354-84-6
Synonyms: PentamethylcyclopentadienylIRidium(III) chloride,dimer
[Ir(Cp-)Cl2]2 is used as a precursor for the asymmetric transfer hydrogenation catalyst of ketones. It is a catalyst for greener amine synthesis .
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Cat. No.: HY-W007596
CAS No.: 94928-86-6
Synonyms: IR(ppy)3; Tris[2-(pyridin-2-yl)phenyl]IRidium
Research Areas:  

Others

Tris(2-phenylpyridinato-C2,N)iridium(III) (Ir(ppy)3) is an iridium(III) containing organometallic complex, which is used as a phosphorescent light-emitting material. Tris(2-phenylpyridinato-C2,N)iridium(III) exhibits high luminous efficiency and good thermal stability, that can be used in organic optoelectronics, especially in improving the luminescence efficiency and stability of organic light-emitting diodes (OLEDs) .
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Cat. No.: HY-P99665
CAS No.: 2131038-11-2
Synonyms: LY-3209590

Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .
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