MHI-148
Based on 1 Customer Validation
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 172971-76-5
- Formula: C42H52BrClN2O4
- Molecular Weight:764.23
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MHI-148 (10 μM, 1 h) is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties[1].
MHI-148 (0-1.5 μM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 172971-76-5
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Appearance Solid
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Molecular Weight 764.23
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Formula C42H52BrClN2O4
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Color Light green to green
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SMILES
CC(C1=CC=CC=C1N/2CCCCCC(O)=O)(C)C2=C/C=C3CCCC(/C=C/C4=[N+](CCCCCC(O)=O)C5=CC=CC=C5C4(C)C)=C\3Cl.[Br-]
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Synonyms
IR-808
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 20.83 mg/mL (27.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3085 mL | 6.5425 mL | 13.0851 mL | 32.7127 mL |
| 5 mM | 0.2617 mL | 1.3085 mL | 2.6170 mL | 6.5425 mL | |
| 10 mM | 0.1309 mL | 0.6543 mL | 1.3085 mL | 3.2713 mL | |
| 15 mM | 0.0872 mL | 0.4362 mL | 0.8723 mL | 2.1808 mL | |
| 20 mM | 0.0654 mL | 0.3271 mL | 0.6543 mL | 1.6356 mL | |
| 25 mM | 0.0523 mL | 0.2617 mL | 0.5234 mL | 1.3085 mL |
MHI-148 Related Classifications
HY-D1711 Related Classifications
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