132 Results for "

Immunomodulators

" in MedChemExpress (MCE) Product Catalog:
Products (132)

132 Results for "Immunomodulators" in MCE Product Catalog:

Cat. No.: HY-13718
CAS No.: 38101-59-6
Purity:  98.97%
Synonyms: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .
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Cat. No.: HY-109854A
CAS No.: 100324-81-0
Purity:  99.99%
Synonyms: (R)-Lisophylline
Target:  

STAT

(R)-Lisofylline ((R)-Lisophylline) is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 μM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research .
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Cat. No.: HY-108842
CAS No.: 215647-85-1
Synonyms: PegIFN a-2b; Sch 54031; Sylatron; ViraferonPeg

Target:  

HIV HCV

Research Areas:  

Infection Cancer

Peginterferon alfa-2b (PegIFN a-2b; Sch 54031; Sylatron; ViraferonPeg) is an immunomodulator. Peginterferon alfa-2b is a recombinant alfa-2b interferon covalently linked PEG with antiviral activity against HCV. Peginterferon alfa-2b decreases viral DNA in HIV. Peginterferon alfa-2b can be used in research of melanoma and hepatitis C .
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Cat. No.: HY-P99295
CAS No.: 959963-46-3
Synonyms: RG 7160; RO 5083945; Anti-EGFR Recombinant Antibody

Target:  

EGFR

Research Areas:  

Cancer

Imgatuzumab (RG 7160) is a humanized monoclonal antibody against the EGFR. Imgatuzumab acts as an immunomodulator. Imgatuzumab can be used in research of cancer .
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Cat. No.: HY-13666S
CAS No.: 1246819-64-6
Synonyms: (-)-Tetramisole-d5 hydrochloride
Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV .
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Cat. No.: HY-125390
CAS No.: 226907-52-4
Purity:  99.41%
Synonyms: CL-087
Research Areas:  

Inflammation/Immunology Cancer

SM-360320 (CL-087) is a potent, orally active TLR7 agonist. SM-360320 is a immuno-modulator and exerts an antitumor effect. SM-360320 can act in synergy with DNA vaccines leading to an enhanced Th1 antibody response . SM-360320 can inhibit HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity .
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Cat. No.: HY-147218
CAS No.: 2412356-57-9
Purity:  97.13%
Synonyms: ARRY-067
Target:  

TAM Receptor

Research Areas:  

Cancer

PF-07265807 (ARRY-067) is a kinase inhibitor with primary targets AXL, MERTK, and TYRO3. PF-07265807 acts as an immunomodulator that cross-activates CD8 + T cells by enhancing dendritic cell function. PF-07265807 blocks downstream signal transduction of AXL and MERTK, and inhibits the proliferation and migration of tumor cells with high expression of these two kinases. PF-07265807 is applicable to research related to advanced or metastatic solid tumors, such as colorectal cancer .
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Cat. No.: HY-106901A
CAS No.: 34433-31-3
Purity:  98.47%
Synonyms: HI-6
Research Areas:  

Neurological Disease

Asoxime dichloride (HI-6) is an orally active thiosemicarbazone-based antidote. Asoxime dichloride is a reversible inhibitor of AChE, and its core mechanism of action is to re-activate AChE inhibited by nerve toxins, thereby restoring the cholinergic nerve function. Asoxime dichloride significantly restores the function of poisoned muscles without reactivating AChE. Asoxime dichloride is an antagonist of acetylcholine receptors (AChRs), including nicotinic receptor and α7 nAChR. Asoxime dichloride can serve as an effective immunomodulator, improving the immune effect of the nervous system .
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Cat. No.: HY-P10056
CAS No.: 174641-44-2
Synonyms: Human ezrin peptide (324-337)
HEP-1 (Human ezrin peptide (324 - 337)) is an orally active peptide with antiviral, anti-inflammatory, and immunomodulatory activities. HEP-1 is effective against infections by various viruses such as HIV, HCV, herpes viruses, HPV, and influenza viruses. As an immunomodulator, HEP-1 can enhance the adaptive immunity mediated by B cells and T cells. HEP-1 can also increase the antibody titers after hepatitis B vaccination. HEP-1 can be used in the research of viral infections and inflammation-related diseases .
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Cat. No.: HY-P99611
CAS No.: 167816-91-3
Synonyms: 64G12

Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

Faralimomab (64G12) is an immunomodulator, and a murine anti-IFNA1 IgG1 mAb .
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Cat. No.: HY-P99215
CAS No.: 1312797-14-0
Synonyms: Anti-EGFL7; RG 7414

Target:  

VEGFR

Research Areas:  

Cancer

Parsatuzumab (Anti-EGFL7; RG 7414) is a humanized monoclonal antibody, acts as an immunomodulator and binds to EGFL7. Parsatuzumab selectively blocks the interaction between EGFL7 and endothelial cells, potentially inhibiting vascular regrowth and reducing vascular endothelial growth factor (VEGF) inhibition .
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Cat. No.: HY-101813
CAS No.: 147076-36-6
Purity:  99.76%
Synonyms: HR325
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
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Cat. No.: HY-124411
CAS No.: 63329-53-3
Purity:  99.42%
Research Areas:  

Inflammation/Immunology

Lobenzarit, an immunomodulator, possesses anti-oxidative .
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Cat. No.: HY-150734A
Purity:  93.51%
Research Areas:  

Infection

ODN 2007 sodium, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 sodium can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .
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Cat. No.: HY-B1044
CAS No.: 20098-14-0
Synonyms: Kemantane; 5-Hydroxy-2-adamantanone
Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an adamantane-based immunomodulator. Idramantone increases the activity of T helper cells by 1.5 to 2-fold, but exerts no significant effect on the functional activity, induction or accumulation of antigen-specific T suppressor cells. Idramantone serves as a key intermediate for the synthesis of various adamantane derivatives, and can be produced via the regioselective oxidation of 2-adamantanone catalyzed by P450cam monooxygenase, a process that relies on an NADH regeneration system to provide reducing equivalents. Idramantone can be used in studies related to immunomodulation .
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Cat. No.: HY-13666R
CAS No.: 16595-80-5
Synonyms: (-)-Tetramisole hydrochloride (Standard)
Levamisole (hydrochloride) (Standard) is the analytical standard of Levamisole (hydrochloride). This product is intended for research and analytical applications. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
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Cat. No.: HY-148801
CAS No.: 2097854-81-2
Synonyms: VTX002
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

Tamuzimod is a potent immunomodulator. Tamuzimod has S1P Receptor modulatory activity with an EC50 of <1 μM .
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Cat. No.: HY-N15156
CAS No.: 2937-54-4
Thiotaurine is the metabolite of Cystine. Thiotaurine is a sulfur donor, which may probably modulates the activity of GAPDH, followed by the pparticipation in neutrophil activation and leukocytes energy metabolism. Thiotaurine is a potential anti-inflammatory agent and immunomodulator .
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Cat. No.: HY-124863A
CAS No.: 241476-71-1
Target:  

SphK

Research Areas:  

Inflammation/Immunology

(R)-AAL is an immunomodulator. (R)-AAL decreases circulating T lymphocytes in rats, with an ID50 value of 0.009 mg/kg. (R)-AAL is a substrate of sphingosine kinase (SphK), which catalyzes the phosphorylation of (R)-AAL .
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Cat. No.: HY-10984A
CAS No.: 202271-89-4
Synonyms: (S)-CC-4047
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies .
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