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Cat. No.: HY-10984A

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(S)-Pomalidomide

(Synonyms: (S)-CC-4047)

(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurK_itt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies.

For research use only. We do not sell to patients.

CAS No.: 202271-89-4
Formula: C₁₃H₁₁N₃O₄
Molecular Weight:273.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(S)-Pomalidomide Chemical Structure

CAS No.: 202271-89-4

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Sample (0.1mg)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
PBMC	IC₅₀	3.9 nM Compound: (S)-5a	Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC	[PMID: 10386948]

Chemical Information

CAS No. 202271-89-4
Molecular Weight 273.24
Formula C₁₃H₁₁N₃O₄
SMILES

O=C1N([C@@H](CC2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
Synonyms

(S)-CC-4047
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Modeling and simulation to probe the pharmacokinetic disposition of pomalidomide R- and S-enantiomers

Calculators

Molarity Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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