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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
79 Results for "
SSTRs
" in MedChemExpress (MCE) Product Catalog:
Products (79)
79 Results for "SSTRs" in MCE Product Catalog:
Cat. No.: HY-P10741
CAS No.: 2151063-66-8
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Cat. No.: HY-P1139
CAS No.: 485803-62-1
Synonyms: PCFWKTCK
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Cat. No.: HY-142701
CAS No.: 2747928-27-2
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SSTR4 agonist 4 is a somatostatin receptor 4 (SSTR4) agonist. SSTR4 agonist 4 functionally activates SSTR4. SSTR4 agonist 4 has the potential for the research of pain .
Synonyms: MK 678 acetate; L 36358 acetate
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Cardiovascular Disease Neurological Disease Metabolic Disease
Cat. No.: HY-P0024A
CAS No.: 2126831-23-8
Synonyms: DG3173 TFA; PTR-3173 TFA
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Cat. No.: HY-P3124
CAS No.: 182153-96-4
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Cat. No.: HY-177493
CAS No.: 3086695-73-7
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SSTR3 Agonist-1 (Compound EX 38) is an orally active SSTR3 agonist, with an EC50 of 0.14 nM. SSTR3 Agonist-1 reduces the kidney cystic index. SSTR3 Agonist-1 can be used in the research of autosomal dominant polycystic kidney disease .
Cat. No.: HY-P3618
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Cat. No.: HY-P3294
CAS No.: 778630-77-6
Synonyms: BIM-23A760; TBR-760
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Cat. No.: HY-P0024
CAS No.: 252845-37-7
Synonyms: DG3173; PTR-3173
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Cat. No.: HY-P2434
CAS No.: 846569-60-6
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Cat. No.: HY-177493A
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SSTR3 agonist-1 TFA is a potent, orally active, and selective SSTR3 agnoist (EC50 =0.14 nM). SSTR3 agonist-1 TFA binds to SSTR3 receptor to inhibit cAMP activity. SSTR3 agonist-1 TFA decreases kidney weight and kidney cystic index (KCI) in a mouse model of autosomal dominant polycystic kidney disease (ADPKD). SSTR3 agonist-1 TFA can be used for ADPKD research .
Cat. No.: HY-P4555
CAS No.: 340821-13-8
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Cat. No.: HY-172147
CAS No.: 2761347-44-6
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SSTR4 agonist 5 (Compound 5) is the orally active agonist for somatostatin receptor 4 (SSTR4) with an EC50 of 0.228 nM. SSTR4 agonist 5 exhibits good stability in human/rat liver microsomes. SSTR4 agonist 5 inhibits mechanical hyperalgesia in rat models .
Cat. No.: HY-160176
CAS No.: 1007836-12-5
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SSTR5 antagonist 6 is an orally active somatostatin receptor subtype 5 (SSTR5) antagonist with an IC50 of 24 nM. SSTR5 antagonist 6 can be used in the study of type 2 diabetes .
Cat. No.: HY-142700
CAS No.: 2744188-34-7
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SSTR4 agonist 3 is a potent agonist of SSTR4. SSTR4 is expressed at relatively high levels in the hippocampus and neocortex, memory and learning regions, and Alzheimer's disease pathology. SSTR4 agonists are potent in rodent models of pain associated with acute and chronic associated anti-peripheral nociceptive and anti-inflammatory activity. SSTR4 agonist 3 has the potential for the research of pain (extracted from patent WO2021233427A1, compound 14) .
Cat. No.: HY-12819
CAS No.: 1235995-16-0
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MK-1421 is a potent and selective sstr3 antagonist. MK-1421 regulates insulin secretion by binding to the sstr3. MK-1421 can be used in the research of type 2 diabetes .
Cat. No.: HY-P2545
CAS No.: 59481-23-1
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Cat. No.: HY-159825
CAS No.: 2412849-26-2
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Branosotine (compound 1-1) is a potent agonist of somatostatin receptor (SSTR2), with the EC50 of ＜0.1 nM .
Cat. No.: HY-114133
CAS No.: 161982-62-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
