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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
gravis
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "gravis" in MCE Product Catalog:
Art. -Nr.: HY-P990818
Target:
Forschungsgebiete:
Target:
Forschungsgebiete:
AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis .
Art. -Nr.: HY-N5077R
CAS. Nr.: 18696-26-9
Category:
Alkaloids Monophenols Other Alkaloids Cruciferae Phenols Plants
Art. -Nr.: HY-N6619A
CAS. Nr.: 21133-52-8
Art. -Nr.: HY-148412
CAS. Nr.: 864021-55-6
Synonyms: EN101; ODN 7040; BL 7040
Target:
Forschungsgebiete:
Monarsen (EN101) is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).
Art. -Nr.: HY-B0882S
Art. -Nr.: HY-119792A
CAS. Nr.: 588-17-0
Target:
Forschungsgebiete:
Neostigmine hydroxide is a cholinesterase inhibitor and can be used for study of myasthenia gravis .
Art. -Nr.: HY-W715341
CAS. Nr.: 31034-86-3
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Forschungsgebiete:
RO-1-5237 is a metabolite of Pyridostigmine Bromide, which is a cholinergic and can be used for myasthenia gravis research .
Target:
Art. -Nr.: HY-W715341R
CAS. Nr.: 31034-86-3
Target:
Forschungsgebiete:
RO-1-5237 (Standard) is the analytical standard of RO-1-5237. This product is intended for research and analytical applications. RO-1-5237 is a metabolite of Pyridostigmine Bromide, which is a cholinergic and can be used for myasthenia gravis research .
Art. -Nr.: HY-119577R
CAS. Nr.: 15876-67-2
Synonyms: Distigmine dibromide (Standard)
Forschungsgebiete:
Ubretid (Standard) is the analytical standard of Ubretid. This product is intended for research and analytical applications. Ubretid is a potent inhibitor of plasma cholinesterase. Ubretid therefore delays the hydrolysis of suxamethonium and prolongs its action, similar to the effects shown by other anticholinesterase agents, such as pyridostigmine and donepezil. Ubretid has the potential for the research of urinary retention prolongs the effect of suxamethonium. Ubretid is commonly prescribed for the research of myasthenia gravis and for difficulty in emptying the bladder .
Category:
Alkaloids other families Monophenols Neurological Disease Phenols Plants Disease Research Fields Inflammation/Immunology
Target:
Art. -Nr.: HY-N6619
CAS. Nr.: 89505-76-0
Category:
Category:
Alkaloids Monophenols Other Alkaloids Cruciferae Phenols Plants
Synonyms: Eustigmin bromide (Standard); Neoserine bromide (Standard)
Forschungsgebiete:
Neostigmine (Bromide) (Standard) is the analytical standard of Neostigmine (Bromide). This product is intended for research and analytical applications. Neostigmine Bromide is a cholinesterase inhibitor that acts on myasthenia gravis.
Art. -Nr.: HY-148412A
Synonyms: EN101 sodium; ODN 7040 sodium; BL 7040 sodium
Target:
Forschungsgebiete:
Monarsen sodium is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen sodium is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).
Target:
Forschungsgebiete:
Neostigmine iodide is a reversible acetylcholinesterase inhibitor with muscle tone-enhancing activity. Neostigmine iodide is primarily used to improve muscle function in patients with myasthenia gravis. Neostigmine iodide is also used in routine anesthesia to reverse the effects of nondepolarizing muscle relaxants such as rocuronium .
Art. -Nr.: HY-151927
Target:
Forschungsgebiete:
AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM .
Art. -Nr.: HY-118533A
CAS. Nr.: 52022-31-8
Synonyms: WIN 8077 dichloride tetrahydrate
Target:
Forschungsgebiete:
Ambenonium (WIN 8077) dichloride tetrahydrate is an orally active and reversible inhibitor of Acetyicholinesterase (AChE) with high affinity. Ambenonium dichloride tetrahydrate inhibits human AChE with an IC50 value of 0.7 nM (hAChE) .
Forschungsgebiete:
Edrophonium chloride (Standard) is the analytical standard of Edrophonium chloride (HY-B0882). This product is intended for research and analytical applications. Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has Ki values of 0.2, 0.2, and 0.4 μM and IC50 values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
