AChE-IN-28
AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM.
For research use only. We do not sell to patients.
- Formula: C33H48BrF3N5O4
- Molecular Weight:715.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE 0.2 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Wistar rats, experimental autoimmune model of myasthenia gravis (EAMG)[1]
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Dosage:0.005, 0.01, 0.015 and 0.1 mg/kg
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Administration:Intraperitoneal injection, single dose
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Result:The dose that restored the value of decrement of amplitude of APs in animals with EAMG to the level of control rats was 0.01 mg/kg. Showed a long lasting effect and had no significant effect on the force of urinary bladder contractions in animals with EAMG.
Chemical Information
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Molecular Weight 715.66
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Formula C33H48BrF3N5O4
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SMILES
CC[N+](CCCCCN1C(C=CN(C1=O)CCCCCCN(C(C=C2=O)C)C(N2C)=O)=O)(CC3=CC=CC=C3C(F)(F)F)CC.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-28 Related Classifications
HY-151927 Related Classifications
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