2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE-IN-27

AChE-IN-27 

Cat. No.: HY-148108 Purity: 98.27%
COA Handling Instructions

AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis.

For research use only. We do not sell to patients.

AChE-IN-27 Chemical Structure

AChE-IN-27 Chemical Structure

CAS No. : 177028-90-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 253 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 253 In-stock
Solid
5 mg USD 230 In-stock
10 mg USD 350 In-stock
25 mg USD 650 In-stock
50 mg USD 975 In-stock
100 mg USD 1550 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].

Molecular Weight

330.34

Appearance

Solid

Formula

C20H14N2O3
CAS No.
SMILES

N#CC(C1C2=CC=C(C)C=C2)=C(N)OC(C3=CC=CC=C3O4)=C1C4=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (302.72 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0272 mL 15.1359 mL 30.2718 mL
5 mM 0.6054 mL 3.0272 mL 6.0544 mL
10 mM 0.3027 mL 1.5136 mL 3.0272 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

AChE-IN-27177028-90-9Cholinesterase (ChE)neurological diseasesalzheimer's diseasedementiaataxiamyasthenia gravisInhibitorinhibitorinhibit

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