60 Results for "

oat

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "oat" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-120107
CAS No.: 1799548-33-6
Target:  

Parasite

Research Areas:  

Inflammation/Immunology

OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC50=14.2 nM for human AMCase and IC50=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis .
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Cat. No.: HY-N8279
CAS No.: 62213-14-3
Synonyms: Endo-β-1,3-1,4-glucanase
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

β-1,3-1,4-glucanase (Endo-β-1,3-1,4-glucanase) is a glycoside hydrolase family 16 enzyme (some members belong to subfamily 25). β-1,3-1,4-glucanase shows high substrate specificity toward mixed‑linked β‑glucans and cleaves β‑1,4 glycosidic bonds adjacent to β‑1,3 linkages in an endo‑type pattern. β-1,3-1,4-glucanase can be used in industrial enzyme applications and monogastric animal feed supplementation .
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Cat. No.: HY-15592R
CAS No.: 1051375-10-0
Synonyms: GSK-1265744 (Standard); S/GSK1265744 (Standard)
Research Areas:  

Infection

Cabotegravir (Standard) is the analytical standard of Cabotegravir. This product is intended for research and analytical applications. Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS .
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Cat. No.: HY-W740244
CAS No.: 53818-10-3
Target:  

OAT

Research Areas:  

Metabolic Disease

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM).
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Cat. No.: HY-111345A
CAS No.: 1198153-46-6
Synonyms: UR-1102 hydrochloride; URC-102 hydrochloride
Target:  

OAT URAT1

Epaminurad (UR-1102) hydrochloride is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad hydrochloride quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad hydrochloride is a uricosuric agent. Epaminurad hydrochloride can be used for gout and hyperuricemia research .
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Cat. No.: HY-W016415
CAS No.: 612-37-3
7-Methyluric acid is a methylated purine metabolite of Theobromine (HY-N0138) and Caffeine. 7-Methyluric acid is a substrate of OAT1 (SLC22A6) and OAT3 (SLC22A8). 7-Methyluric acid is not transported by OATP1B1, OATP1B3, OCT2, MATE1, or P-glycoprotein. 7-Methyluric acid can be used in studies on urolithiasis .
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Cat. No.: HY-144305
CAS No.: 2760615-09-4
Purity:  99.22%
Target:  

URAT1 GLUT

Research Areas:  

Infection

KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM) .
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Cat. No.: HY-N12007
CAS No.: 38393-73-6
OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage .
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Cat. No.: HY-N12008
CAS No.: 2195434-05-8
OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage .
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Cat. No.: HY-161169
CAS No.: 2865102-08-3
Target:  

MMP

Research Areas:  

Cancer

TP0628103 is a potent and highly selective MMP-7 inhibitor with an IC50 of 0.17 nM. TP0628103 undergoes structural optimization via molecular isoelectric point shifting, which reduces organic anion transporter (OAT)-mediated clearance, while maintaining potent MMP-7 inhibitory activity and enhancing MMP subtype selectivity. TP0628103 is applicable for research on the regulatory mechanisms of MMP-7-related matrix metalloproteinases .
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Cat. No.: HY-125279
CAS No.: 2221950-65-6
Target:  

Parasite

Research Areas:  

Inflammation/Immunology

OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases .
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Cat. No.: HY-RS09731
Research Areas:  

Others

OAT Human Pre-designed siRNA Set A contains three designed siRNAs for OAT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16776
Research Areas:  

Others

Oat Mouse Pre-designed siRNA Set A contains three designed siRNAs for Oat gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-15258S1
CAS No.: 1850305-60-0
Synonyms: RDEA594-d4
Lesinurad-d4 (RDEA594-d4) is deuterium labeled Lesinurad. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 μM, respectively.
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Cat. No.: HY-129493
CAS No.: 93752-78-4
Lateropyrone is a type of pyranone antibiotic that can inhibit Gram-negative bacteria, and it's a secondary metabolite produced by the oat fungal pathogen .
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Cat. No.: HY-136367
CAS No.: 51338-27-3
Purity:  99.95%
Research Areas:  

Others

Diclofop-methyl, a common post-emergence herbicide, is widely used in agriculture production. Diclofop-methyl increases the proton permeability of isolated oat-root tonoplast .
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Cat. No.: HY-163431
CAS No.: 3012586-38-5
Target:  

URAT1

Research Areas:  

Inflammation/Immunology

URAT1 inhibitor 10 (Compound 23a) is a URAT1 inhibitor. URAT1 inhibitor 10 has oral efficacy and low cytotoxicity. URAT1 inhibitor 10 has high selectivity for OAT1 .
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Cat. No.: HY-W014118R
CAS No.: 101-86-0
α-Hexylcinnamaldehyde (Standard) is the analytical standard of α-Hexylcinnamaldehyde. This product is intended for research and analytical applications. α-Hexylcinnamaldehyde is an O-acetyltransferase (OAT) inhibitor. α-Hexylcinnamaldehyde inhibits OAT-mediated bioactivation of nitroarene mutagens, exerts antimutagenic activity through demutagenic and bioantimutagenic mechanisms, and interferes with ATP-binding cassette (ABC) transporter function to reduce substrate efflux. α-Hexylcinnamaldehyde alters membrane permeability, fluidizes phospholipid membranes, exerts antioxidant effects, and enhances the antiproliferative effect of Doxorubicin on human cancer cells. α-Hexylcinnamaldehyde can be used in the research of colorectal adenocarcinoma, T-cell leukemia, and multidrug-resistant cancers .
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Cat. No.: HY-126987R
CAS No.: 208465-21-8
Research Areas:  

Others

Mesosulfuron-methyl (Standard) is the analytical standard of Mesosulfuron-methyl. This product is intended for research and analytical applications. Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields .
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Cat. No.: HY-N15726
CAS No.: 2414481-40-4
Obtusichromoneside C is a chromone C-glycoside found in the seeds of Cassia obtusifolia. Obtusichromoneside C regulates substance transport by inhibiting substrate uptake of specific transporters (e.g., OAT3, OATP1B3). Obtusichromoneside C is promising for research of drug transport .
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