47 Results for "

Cross-coupling

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "Cross-coupling" in MCE Product Catalog:

Referencia número: HY-101974
No. CAS: 1041766-91-9
Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.
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Referencia número: HY-W002734
No. CAS: 87199-18-6
Synonyms: 3-Hydroxybenzeneboronic acid
Target:  

Drug Intermediate

Áreas de investigación:  

Metabolic Disease

(3-Hydroxyphenyl)boronic acid (3-Hydroxybenzeneboronic acid) is a drug intermediate that can be used for the synthesis of 17β-hydroxysteroid dehydrogenase type 1 inhibitors .
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Referencia número: HY-W048492
No. CAS: 172163-62-1
Synonyms: 7-Deaza-7-Iodo-2'-deoxyguanosine
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a modified deoxyguanosine nucleoside. 7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions .
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Referencia número: HY-W034801
No. CAS: 13395-16-9
Synonyms: Cupric Acetylacetonate
Áreas de investigación:  

Others

Copper(II) acetylacetonate (Cupric Acetylacetonate) is the homoleptic acetylacetonate complex of copper(II). Copper(II) acetylacetonate is used as a catalyst in various organic reactions, including oxidation, cross-coupling, and polymerization reactions. Copper(II) acetylacetonate is also a precursor for making metal-organic frameworks (MOF) and nanomaterials .
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Referencia número: HY-W583317
No. CAS: 2375242-78-5
Áreas de investigación:  

Others

sSPhos Pd G2 is a palladium catalyst with excellent cross-coupling reaction activity. sSPhos Pd G2 exhibits efficient catalytic ability in the synthesis of organic molecules and compounds. sSPhos Pd G2 can effectively promote the formation of CC bonds, optimize reaction conditions and increase yields. sSPhos Pd G2 is also used in a variety of transformation reactions, helping researchers develop new materials and compounds.
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Referencia número: HY-32928
No. CAS: 126747-14-6
Áreas de investigación:  

Others

4-Cyanobenzeneboronic acid is a boronic acid derivative and also coupling reagent in Suzuki cross-coupling reactions .
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Referencia número: HY-P3350
No. CAS: 2892148-58-0
Target:  

Bacterial

Áreas de investigación:  

Infection

LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
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Referencia número: HY-W000873
No. CAS: 146631-00-7
Target:  

Drug Intermediate

Áreas de investigación:  

Metabolic Disease

4-Benzyloxyphenylboronic acid is an arylboronic acid reagent that generates Monobenzone (HY-30272), a compound that inhibits melanin production in the skin, via electrochemical deboronation hydroxylation. 4-Benzyloxyphenylboronic acid serves as a coupling partner in Pd (0)-catalyzed Suzuki-Miyaura cross-coupling reactions for the synthesis of bent-core liquid crystals and liquid crystalline amphiphiles. 4-Benzyloxyphenylboronic acid is used in the study of hyperpigmentation .
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Referencia número: HY-W002463
No. CAS: 63503-60-6
3-Chlorophenylboronic acid is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. 3-Chlorophenylboronic acid is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors among others. 3-Chlorophenyl boronic acid can affect cell migration. 3-Chlorophenyl boronic acid can be used to study wound healing .
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Referencia número: HY-W034606
No. CAS: 1067883-58-2
Synonyms: CM-Phos
2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole (CM-Phos) is an organic compound with catalytic activity. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole can be used as an efficient catalyst for cross-coupling reactions of various alcohols and olefins. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole shows important application potential in pharmaceutical and material science.
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Referencia número: HY-W020985
No. CAS: 31277-98-2
Synonyms: Pd(DIPHOS)2
Bis[1,2-bis(diphenylphosphino)ethane]palladium(0), often abbreviated as Pd(PPh3)2 or Pd(dppf), is an organometallic compound. This compound is widely used as a catalyst for organic chemical reactions, especially cross-coupling reactions such as Suzuki-Miyaura reaction and Heck reaction, and its high catalytic activity, selectivity and stability make it a versatile tool for the synthesis of complex organic compounds , in addition, the potential application of Pd(PPh3)2 in the production of electronic materials and in medical and biochemical research has also been investigated.
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Referencia número: HY-120286
No. CAS: 108890-90-0
K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.
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Referencia número: HY-119928
No. CAS: 479-68-5
Áreas de investigación:  

Cancer

Broparestrol is a biologically active tetrasubstituted olefin can be achieved via palladium-catalyzed cross-coupling to form a C-C bond followed by bromination. Broparestrol inhibits mammary carcinogenesis in mouse model. Broparestrol can be used in dermatology and cancer research .
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Referencia número: HY-W008658
No. CAS: 82499-43-2
[1,4-Bis(diphenylphosphino)butane](norbornadiene)rhodium tetrafluoroborate is a highly efficient and selective transition metal catalyst that can catalyze a variety of reactions, including cross-coupling reactions and hydrogenation reactions. This compound is widely used in organic synthesis and helps to promote the development of new compounds and materials. Through its catalytic activity, [1,4-Bis(diphenylphosphino)butane](norbornadiene)rhodium tetrafluoroborate offers the potential to optimize reaction conditions and improve yields.
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Referencia número: HY-W582827
No. CAS: 2361069-97-6
RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is a highly efficient catalyst with excellent cross-coupling activity. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is widely used in organic synthesis and can be used to promote various reactions to build complex molecular structures. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) has good adaptability to temperature and reaction conditions, which enables it to exhibit excellent catalytic performance in different reaction systems.
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Referencia número: HY-W075744
No. CAS: 2049086-34-0
SK-J002-1n is a highly efficient catalyst with excellent cross-coupling reaction activity. SK-J002-1n is widely used in organic synthesis to construct complex molecular structures. The chiral properties of SK-J002-1n make it play an important role in the pharmaceutical industry and provide support for the synthesis of chiral compounds. SK-J002-1n can significantly improve the conversion efficiency and is an important component of transition metal catalysts.
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Referencia número: HY-P11911
Áreas de investigación:  

Neurological Disease

Cyclo(Val-Val-Ile-d-Ala-Trp(7-Br)-Gly) is a cyclic peptide containing 7-bromotryptophan, designed as a precursor for Sonogashira cross-coupling to generate a BODIPY-conjugated probe selective for prefibrillar 1−42 oligomers .
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Referencia número: HY-175553
Target:  

VEGFR Apoptosis

Áreas de investigación:  

Cancer

VEGFR-2-IN-72 is a selective VEGFR-2 inhibitor with an IC50 of 22.2 nM. VEGFR-2-IN-72 exhibits anticancer activity against HepG2 and Hep3B human HCC cell lines with IC50s of 15.7 and 2.4 μM. VEGFR-2-IN-72 can cause a mild blockage of the cell cycle and induce cell aopoptosis. VEGFR-2-IN-72 can used for the study of hepatocellular carcinoma (HCC) .
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Referencia número: HY-146489
No. CAS: 2521629-86-5
Target:  

Bacterial Parasite

Áreas de investigación:  

Infection

Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .
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Referencia número: HY-146487
No. CAS: 2348-77-8
Target:  

Bacterial Parasite

Áreas de investigación:  

Infection

Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .
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