2348-77-8
Chemical Structure
Anti-infective agent 1
- CAS No.: 2348-77-8
- Formula:C16H10O2
- Molecular Weight:234.25
IUPAC Name: 2-phenylnaphthalene-1,4-dione
InChIKey: CIDYIYSNDAJNGX-UHFFFAOYSA-N
SMILES: O=C1C=C(C(C2=CC=CC=C12)=O)C3=CC=CC=C3
Biological Activity: Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL[1].
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Anti-infective agent 1 | Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL. | |||||||||||||||||||||
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Keywords